Magnetic resonance imaging-guided high intensity focused ultrasound (MR-HIFU) is a non-invasive therapy that uses focused ultrasonic waves to heat tissue in the body and to cause this tissue to coagulate, without damaging the surrounding tissue. During HIFU treatment, the ultrasonic beam penetrates the skin and soft tissue and causes localized high temperatures in the target area only, while ensuring the skin and the surrounding tissue remain intact. The target area for ablation is called the therapy cell. In the case of higher fibroid volumes, ablation is performed by placing multiple therapy cells in the desired target area and treating the cells one by one.

MR-HIFU combines HIFU therapy with magnetic resonance (MR) guidance, thereby enabling the target area to be planned precisely while also monitoring the temperature. MR guidance provides three-dimensional anatomical images as reference data for the treatment plan, while the images from the real-time temperature monitoring can be used to monitor the ablation process.


This site is solely intended for residents of Germany where the SONALLEVE® MR-HIFU has been granted CE Marking and is authorized for sale by applicable health regulatory authorities. This site contains information about treatment options that are not available in every country. Each country has specific laws, regulations, and medical practices governing the communication of information about medical treatments. Nothing on this site should be construed as a solicitation or promotion for any treatment which is not authorized by the laws and regulations of the country where the reader resides. At this time, SONALLEVE is not approved for commercial sale in the USA and does not have FDA clearance. The content of this site is provided for informational purposes only. This site does not provide medical advice nor does it provide instruction on the appropriate use of products. The information on this site is not intended to, and should not, replace or substitute the advice of your physician or other qualified healthcare professional. Absolutely no information contained or accessible through this site should be construed as taking the place of your physician’s advice. You should always discuss any health-related questions with your own physician and other healthcare professionals involved in your treatment and care. Profound Medical is not responsible for any reliance or decisions made by you based on the information available on this site. Do not use this information to diagnose or treat a medical condition or health problem. You should never disregard or delay seeking medical advice because of something that you have seen on this site. Every medical treatment has risks and benefits and no outcome can ever be guaranteed. By accessing or using this site (including all content and functionality), you agree to be bound by the Terms of Use and you also agree to the terms in our Privacy Policy, which explains what information we collect, how we gather and use the information, our policies for protecting and disclosing information, and the options you have regarding your information. If you do not agree with any the Terms of Use or our Privacy Policy, please do not access or use the site.